Your guess is as good as mine
You can’t take it with you
You can catch more flies with honey than with vinegar.
You can’t have your cake and eat it too.
Your name is mud
You show me the man and I’ll show you the rule.
You can’t fit a round peg in a square hole.
You can’t always get what you want.
You can lead a horse to water but you can’t make it drink.
You can’t teach an old dog new tricks.